Self-Assembly in the Ferritin Nano-Cage Protein Superfamily
نویسندگان
چکیده
منابع مشابه
Self-Assembly in the Ferritin Nano-Cage Protein Superfamily
Protein self-assembly, through specific, high affinity, and geometrically constraining protein-protein interactions, can control and lead to complex cellular nano-structures. Establishing an understanding of the underlying principles that govern protein self-assembly is not only essential to appreciate the fundamental biological functions of these structures, but could also provide a basis for ...
متن کاملRe-engineering protein interfaces yields copper-inducible ferritin cage assembly.
The ability to chemically control protein-protein interactions would allow the interrogation of dynamic cellular processes and lead to a better understanding and exploitation of self-assembling protein architectures. Here we introduce a new engineering strategy--reverse metal-templated interface redesign (rMeTIR)--that transforms a natural protein-protein interface into one that only engages in...
متن کاملThe unique self-assembly/disassembly property of Archaeoglobus fulgidus ferritin and its implications on molecular release from the protein cage.
BACKGROUND In conventional in vitro encapsulation of molecular cargo, the multi-subunit ferritin protein cages are disassembled in extremely acidic pH and re-assembled in the presence of highly concentrated cargo materials, which results in poor yields due to the low-pH treatment. In contrast, Archaeoglobus fulgidus open-pore ferritin (AfFtn) and its closed-pore mutant (AfFtn-AA) are present as...
متن کاملNano Wires by Self Assembly
We present a technique to fabricate nano wires on silicon substrates without any lithography. The wires are 50 nm or less in width, but their lengths can be 10s of micro meters. They can be formed by a single or multiple layers of metals. The wires can be designed to form a network which can be partially released from the substrate to form 3D structures. Such structures may serve as actuators o...
متن کاملEngineering Nano-aggregates: β-Cyclodextrin Facilitates the Thiol-Gold Nanoparticle Self-Assembly
The structure and morphology of nonmaterial formed by colloidal synthesis represent a subject of interest as it is a factor deciding the physicochemical properties and biological applications of nanostructures. Among various nanoparticles, gold can develop fractal assembled patterns. Herein, we report a nano-aggregate of a thiol-on-gold self-assembled structure and the influence of β-cyclodextr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2011
ISSN: 1422-0067
DOI: 10.3390/ijms12085406